Prellis-Biologics is a pioneering company in the field of bioprinting and biotechnology, known for its advancements in creating human tissues and organs using 3D printing technology. Here are some detailed points about Prellis-Biologics:
Foundation and Vision
- Founded in 2016, Prellis-Biologics was established with the goal to revolutionize the organ transplant process by developing functional human tissues and organs.
- Their vision is to address the critical shortage of transplantable organs and tissues by producing bioprinted solutions that can integrate into the human body, reducing rejection rates.
Technology
- Prellis-Biologics utilizes a unique high-resolution 3D printing technology known as Holomodule Printing. This technology allows for the printing of microvascular networks, which are essential for the survival and functionality of printed tissues.
- Their approach involves using hydrogel-based bioinks that can support cellular viability, enabling the creation of complex tissue structures.
Key Developments and Milestones
- In 2017, Prellis-Biologics achieved a significant milestone by creating the world's first microvascular network inside a 3D printed structure, a crucial step towards making functional human tissues.
- They have developed vascularized human tissues like liver, heart, and skin, which have potential applications in drug testing, disease modeling, and eventually, organ replacement.
- The company has received funding from notable investors like Khosla Ventures and Founders Fund, highlighting the industry's belief in their technology.
Collaborations and Partnerships
- Prellis-Biologics has collaborated with various research institutions and pharmaceutical companies to advance their technology. For instance, they have worked with UCSD (University of California, San Diego) for research in organ printing.
- They also partner with companies like Bayer to explore applications in drug discovery and development.
Future Prospects
- The company aims to eventually print entire human organs, although this remains a long-term goal due to the complexity involved in replicating all aspects of human organ function.
- Short-term objectives include perfecting smaller tissue constructs for medical applications, such as patches for wound healing or replacements for damaged tissues.
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